Month: January 2024

LONDON, UK / ACCESSWIRE / January 31, 2024 / Ecora Resources PLC (LSE:ECOR)(TSX:ECOR) issues the following trading update for the period 1 October 2023 to 31 December 2023. This update is released ahead of the Group’s audited full year results on 27 March 2024.

Fourth Quarter and Full Year 2023 Portfolio Contribution

FY23 portfolio contribution of $63.6m (2022: $143.2m), with the YoY decline primarily a result of expected lower production within the Group’s private royalty area at Kestrel as well as a normalisation of commodity prices in 2023 from near record levels the previous year. Q4 portfolio contribution was $14.4m (including $5.4m of accrued income). Net debt as at 31 December 2023 was $75m (2022: $36m).

Marc Bishop Lafleche, Chief Executive Officer of Ecora, commented:
"In-line with our expectations, portfolio contribution rebounded from third quarter levels as operations at Kestrel moved back within the Group’s private royalty area and a higher weighting of quarterly cobalt deliveries from Voisey’s Bay.

"This momentum has continued into 2024. Kestrel production within the Group’s private royalty area is expected to increase 15-25% compared to 2023. The Voisey’s Bay underground ramp-up is expected to accelerate in H2, and other volumes across the portfolio expected to be ahead or in-line with last year. Current commodity price levels would imply year-on-year portfolio contribution growth in the year ahead.

"In the fourth quarter, we acquired an incremental royalty interest over the Piauí project for $7.5m. Brazilian Nickel will primarily use these funds to de-risk the project by undertaking detailed engineering studies prior to project construction. This was financed by recycling a portion of our LIORC holding in the quarter, which realised a c. 110% total pre-tax return on the investment.

"The mining sector continues to see underinvestment and a challenging market backdrop. We anticipate these conditions will persist over next 2-3 years, during which royalty financing should be a highly attractive source of capital. The extension of our revolving credit facility puts us in a strong position to continue to grow and diversify our portfolio, which currently offers the leading copper growth profile in the royalty sector."

Highlights:

· FY23 portfolio contribution of $63.6m (2022: $143.2m), with the YoY decline primarily a result of lower production within the Group’s private royalty area at Kestrel as well as a normalisation of commodity prices in 2023 from near record levels the previous year.

· Q4 portfolio contribution was $14.4m (including $5.4m of accrued income released to the income statement following the favourable Four Mile judgment announced on 4 December 2023). On a recurring basis, Q4 portfolio contribution was $9.1m, up 57% on Q3 2023 ($5.8m).

· The Voisey’s Bay stream produced four deliveries in Q4 (Q3 2023: one delivery) taking the number of deliveries for 2023 to 11 (2022: 19 deliveries), in line with guidance and reflecting the ramp up profile of the underground transition.

· During Q4 2023, the Group invested $7.5m into Brazilian Nickel’s Piauí nickel-cobalt project, increasing its royalty by 0.35% to 1.60%.

o The proceeds will primarily be used to finance detailed engineering studies and flow sheet optimisation that will further de-risk the project prior to the start of construction.

o The Group has the right to acquire a further 2.65% royalty over the Piauí project for a consideration of $62.5m. These funds would form part of the construction financing package.

· During Q4, the Group sold ~60% of its residual stake in Labrador Iron Ore Royalty Corporation (LIORC) realising C$18.9m, a total pre-tax return on investment of c. 110% and a gain on disposal of C$4.1m. The proceeds were used to pay down debt and remain available to fund growth opportunities, including the recent investment into Piauí.

· Net debt at the end of the period, following these investment activities, was $75m (2022: $36m).

Portfolio Outlook

· Production at Kestrel moved back into the Group’s private royalty area at the end of 2023. Saleable volumes produced within the Group’s private royalty area are forecast to be 15-25% higher in 2024 than those achieved in 2023 (c 1.6 Mt) and are expected to be weighted towards Q1, with approximately 75% of the full year volumes in Q1, and approximately 15% in Q4. Steelmaking coal prices have started the year at elevated levels compared to the previous year.

· Voisey’s Bay stream is expected to produce between 12-16 deliveries of cobalt in 2024. Between 5-6 deliveries are scheduled for H1 2024, as deliveries will be heavily weighted towards the second half of the year when production from the underground mining operations is expected to ramp up. More detailed guidance for H2 will be provided in the Q2 2024 trading update.

· Mantos Blancos production volumes are forecast to increase in 2024 due to higher mill throughput with the increase being second half weighted.

· Capstone Copper is expecting to release a Feasibility Study for the Santo Domino project by mid-2024, with a potential project sanctioning decision not anticipated prior to mid-2025.

· BHP continues construction of the West Musgrave nickel-copper project in Australia with first production targeted as early as end-2025.

· Production volumes at the Group’s other royalty assets for 2024 are expected to be broadly in line with 2023 levels.

Post Period Events

· In January 2024, the Group made the final $9.2m deferred consideration payment to South32 in relation to the royalty portfolio acquired in 2022.

· Completion of a refinancing of the Group’s corporate debt facilities has increased the borrowing potential to $225m on broadly similar terms to the previous facility.

⁽¹⁾The portfolio contribution above is unaudited and based on narrow midpoint range, therefore, the actual number reported in the forthcoming annual report may be slightly higher or lower.

⁽²⁾ Under IFRS 9, the royalties received from EVBC are reflected in the fair value movement of the underlying royalty rather than recorded as royalty income.

⁽³⁾ Four Mile Q4 revenue includes A$8.1m (US$5.4m) of previously underpaid royalties recognised as a result of the Appeal being upheld in December 2023

For further information

About Ecora Resources

Ecora Resources is a leading royalty company focused on supporting the supply of commodities essential to creating a sustainable future.

Our vision is to be globally recognised as the royalty company of choice synonymous with commodities that support a sustainable future by continuing to grow and diversify our royalty portfolio in line with our strategy. We will achieve this through building a diversified portfolio of scale over high quality assets that drives low volatility earnings growth and shareholder returns.

The mining sector has an essential role to play in the energy transition, with commodities such as copper, nickel and cobalt – key materials for manufacturing batteries and electric vehicles. Copper also plays a critical role in our electricity grids. All these commodities are mined and there are not enough mines in operation today to supply the volume required to achieve the energy transition.

Our strategy is to acquire royalties and streams over low-cost operations and projects with strong management teams, in well-established mining jurisdictions. Our portfolio has been reweighted to provide material exposure to this commodity basket and we have successfully transitioned from a coal orientated royalty business in 2014 to one that by 2026 will be materially coal free and comprised of over 90% exposure to commodities that support a sustainable future. The fundamental demand outlook for these commodities over the next decade is very strong, which should significantly increase the value of our royalty portfolio.

Ecora’s shares are listed on the London and Toronto Stock Exchanges (ECOR) and trade on the OTCQX Best Market (OTCQX: ECRAF).

Cautionary statement on forward-looking statements and related information
Certain statements in this announcement, other than statements of historical fact, are forward-looking statements based on certain assumptions and reflect the Group’s expectations and views of future events. Forward-looking statements (which include the phrase ‘forward-looking information’ within the meaning of Canadian securities legislation) are provided for the purposes of assisting readers in understanding the Group’s financial position and results of operations as at and for the periods ended on certain dates, and of presenting information about management’s current expectations and plans relating to the future. Readers are cautioned that such forward-looking statements may not be appropriate other than for purposes outlined in this announcement. These statements may include, without limitation, statements regarding the operations, business, financial condition, expected financial results, cash flow, requirement for and terms of additional financing, performance, prospects, opportunities, priorities, targets, goals, objectives, strategies, growth and outlook of the Group including the outlook for the markets and economies in which the Group operates, costs and timing of acquiring new royalties and making new investments, mineral reserve and resources estimates, estimates of future production, production costs and revenue, future demand for and prices of precious and base metals and other commodities, for the current fiscal year and subsequent periods.

Forward-looking statements include statements that are predictive in nature, depend upon or refer to future events or conditions, or include words such as ‘expects’, ‘anticipates’, ‘plans’, ‘believes’, ‘estimates’, ‘seeks’, ‘intends’, ‘targets’, ‘projects’, ‘forecasts’, or negative versions thereof and other similar expressions, or future or conditional verbs such as ‘may’, ‘will’, ‘should’, ‘would’ and ‘could’. Forward-looking statements are based upon certain material factors that were applied in drawing a conclusion or making a forecast or projection, including assumptions and analyses made by the Group in light of its experience and perception of historical trends, current conditions and expected future developments, as well as other factors that are believed to be appropriate in the circumstances. The material factors and assumptions upon which such forward-looking statements are based include: the stability of the global economy; the stability of local governments and legislative background; the relative stability of interest rates; the equity and debt markets continuing to provide access to capital; the continuing of ongoing operations of the properties underlying the Group’s portfolio of royalties, streams and investments by the owners or operators of such properties in a manner consistent with past practice; no material adverse impact on the underlying operations of the Group’s portfolio of royalties, streams and investments from a global pandemic; the accuracy of public statements and disclosures (including feasibility studies, estimates of reserve, resource, production, grades, mine life and cash cost) made by the owners or operators of such underlying properties; the accuracy of the information provided to the Group by the owners and operators of such underlying properties; no material adverse change in the price of the commodities produced from the properties underlying the Group’s portfolio of royalties, streams and investments; no material adverse change in foreign exchange exposure; no adverse development in respect of any significant property in which the Group holds a royalty or other interest, including but not limited to unusual or unexpected geological formations and natural disasters; successful completion of new development projects; planned expansions or additional projects being within the timelines anticipated and at anticipated production levels; and maintenance of mining title.

Forward-looking statements are not guarantees of future performance and involve risks, uncertainties and assumptions, which could cause actual results to differ materially from those anticipated, estimated or intended in the forward-looking statements. Past performance is no guide to future performance and persons needing advice should consult an independent financial adviser. No statement in this communication is intended to be, nor should it be construed as, a profit forecast or a profit estimate.

By its nature, this information is subject to inherent risks and uncertainties that may be general or specific and which give rise to the possibility that expectations, forecasts, predictions, projections or conclusions will not prove to be accurate; that assumptions may not be correct and that objectives, strategic goals and priorities will not be achieved.

A variety of material factors, many of which are beyond the Group’s control, affect the operations, performance and results of the Group, its businesses and investments, and could cause actual results to differ materially from those suggested by any forward-looking information. Such risks and uncertainties include, but are not limited to current global financial conditions, royalty, stream and investment portfolio and associated risk, adverse development risk, financial viability and operational effectiveness of owners and operators of the relevant properties underlying the Group’s portfolio of royalties, streams and investments; royalties, streams and investments subject to other rights, and contractual terms not being honoured, together with those risks identified in the ‘Principal Risks and Uncertainties’ section of our most recent Annual Report, which is available on our website. If any such risks actually occur, they could materially adversely affect the Group’s business, financial condition or results of operations. Readers are cautioned that the list of factors noted in the section herein entitled ‘Risk’ is not exhaustive of the factors that may affect the Group’s forward-looking statements. Readers are also cautioned to consider these and other factors, uncertainties and potential events carefully and not to put undue reliance on forward-looking statements.

The Group’s management relies upon this forward-looking information in its estimates, projections, plans and analysis. Although the forward-looking statements contained in this announcement are based upon what the Group believes are reasonable assumptions, there can be no assurance that actual results will be consistent with these forward-looking statements. The forward-looking statements made in this announcement relate only to events or information as of the date on which the statements are made and, except as specifically required by applicable laws, listing rules and other regulations, the Group undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events.

This announcement also contains forward-looking information contained and derived from publicly available information regarding properties and mining operations owned by third parties. This announcement contains information and statements relating to the Kestrel mine that are based on certain estimates and forecasts that have been provided to the Group by Kestrel Coal Pty Ltd ("KCPL"), the accuracy of which KCPL does not warrant and on which readers may not rely.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: Ecora Resources PLC

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Ondine Biomedical demonstrated that photodisinfection does not harm the nasal microbiome

VANCOUVER, BC / ACCESSWIRE / January 31, 2024 / Research presented by Canadian life sciences company, Ondine Biomedical Inc. ("Ondine Biomedical", "Ondine", or the "Company") (LON:OBI), at the prestigious SPIE Photonics West conference in San Francisco, California shows that treatment with its Steriwave^® Nasal Photodisinfection System significantly reduces pathogens in the nose – a reservoir for bacteria – yet does not produce long-term adverse effects on the nasal microbiome.^[*]

Upon analysis of nasal swab samples, the research demonstrated an immediate and highly significant (99.9+% ~3 log₁₀) reduction in viable bacterial cells and number of species, sustained for at least 24 hours. Importantly, within a week, the microbiome rebounded to its original diversity and quantity. These findings support Steriwave as an efficient, potent, short-acting, and non-selective method of nasal decolonization, with the advantage of rapid recovery of the native microbiome post-treatment.

In comparison to antibiotics, the study demonstrated that Steriwave is far less likely to significantly alter the native microbiota. The antibiotic mupirocin, commonly used for nasal decolonization, has been shown to affect microbiota diversity for over 6 months, allowing disease-causing pathogens like Staphylococcus aureus to colonize the nose before beneficial species, putting patients at increased risk of infection.^[1] Steriwave, in contrast, offers a more favourable profile with the study results showing a reduced risk of long-term microbiome disruption, as the microbiome consistently returns to baseline.

Notably, minimizing microbiome disruption is also important in safeguarding immune function, reducing vulnerability to infectious diseases by maintenance of a microecological environment populated by beneficial commensal microbes instead of disease-causing species.^[2] The oral research presentation, delivered by Ondine’s Director of Research and Development, Dr. Caetano Sabino, reported results from an exploratory study involving 35 healthy volunteers, examining the responses of the nasal microbial population after Steriwave treatment.

Organized by SPIE, the international society for optics and photonics, SPIE Photonics West is the largest annual event for optic and photonic technologies and one of the world’s largest scientific conferences. Ondine’s oral presentation, titled "Microbiome Analysis of Photodynamic Nasal Decolonization," was delivered at 10:20am on Tuesday 30 January, as part of the "Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases" session.

**ENDS**

About SPIE Photonics West

SPIE Photonics West is the optics and photonics industry’s preeminent annual conference and exhibition and is one of the largest scientific conferences in the world. Its scope covers all areas regarding the use of light for scientific and technological applications. The conference brings together tens of thousands of researchers, innovators, engineers, and business leaders from across the globe for an engaging week of research sharing, collaboration forming, and innovation-inspiring exchanges. The week will include more than 4,500 technical presentations as well as showcasing over 1,200 companies in three focused exhibitions.

About Ondine Biomedical Inc.

Ondine Biomedical Inc. is a Canadian life science company innovating in the field of photodisinfection therapies. Ondine has a pipeline of investigational products, based on its proprietary photodisinfection platform, in various stages of development. Ondine’s nasal photodisinfection system has a CE mark in Europe and the UK and is approved in Canada and several other countries under the name Steriwave®. In the US, it has been granted Qualified Infectious Disease Product designation and Fast Track status by the FDA and is currently undergoing clinical trials for regulatory approval. Products beyond nasal photodisinfection include therapies for a variety of medical indications such as chronic sinusitis, ventilator-associated pneumonia, burns, and other indications.

About Nasal Photodisinfection

Ondine’s Steriwave® Nasal Photodisinfection System is a patented technology using a proprietary light-activated antimicrobial (photosensitizer) to destroy pathogens. The photodisinfection treatment is carried out by a trained healthcare professional and is an easy to use, painless, two-step process. The photosensitizer is applied to each nostril using a nasal swab, followed by illumination of the area with a specific wavelength of red laser light for less than five minutes. The light activates the photosensitizer, causing an oxidative burst that is lethal to all types of pathogens. A key benefit of this approach, unlike with antibiotics, is that pathogens do not develop resistance to the therapy.

Nasal decolonization with antibiotics is already standard practice in many hospitals prior to surgery, as pathogens in a patient’s nasal cavities are a major cause of surgical site infections (SSIs). Nasal decolonization is recommended in the 2016 WHO Global guidelines for the prevention of surgical site infections,^[3] and the Society for Healthcare Epidemiology of America (SHEA) guidelines, published in May 2023, recommend nasal decolonization for major surgical procedures.^[4] However, there is a growing need to reduce antibiotic use and find non-antibiotic methods of nasal decolonization as resistance rates have been reported as high as 81%.^[5]

^[*] The nasal microbiome consists of a complex community of microorganisms – fungi, parasites, viruses, and bacteria – that can act in a symbiotic relationship in the nasal cavity.

^[1] Baede VO, Barray A, Tavakol M, Lina G, Vos MC, Rasigade JP. Nasal microbiome disruption and recovery after mupirocin treatment in Staphylococcus aureus carriers and noncarriers. Sci Rep. 2022 Nov 17;12(1):19738. doi: 10.1038/s41598-022-21453-4. PMID: 36396730; PMCID: PMC9671894.

^[2] Cho I, Blaser MJ. The human microbiome: At the interface of health and disease. Nat Rev Genet. 2012; 13: 260.

Arrieta M-C, Stiemsma LT, Amenyogbe N, Brown EM, Finlay B. The intestinal microbiome in early life: Health and disease. Front Immunol. 2014; 5: 427.

DeGruttola AK, Low D, Mizoguchi A, Mizoguchi E. Current understanding of dysbiosis in disease in human and animal models. Inflamm Bowel Dis. 2016; 22: 1137-1150.

^[3] https://cdn.who.int/media/docs/default-source/integrated-health-services-(ihs)/ssi/fact-sheet-staphylococcus-web.pdf?sfvrsn=7e7266ed_2

^[4] Calderwood MS, Anderson DJ, Bratzler DW, et al. Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update. Infect Control Hosp Epidemiol. 2023;44(5):695-720. doi:10.1017/ice.2023.67

^[5] Poovelikunnel T, Gethin G, Humphreys H. Mupirocin resistance: clinical implications and potential alternatives for the eradication of MRSA. J Antimicrob Chemother. 2015;70(10):2681-2692. doi:10.1093/jac/dkv169

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SOURCE: Ondine Biomedical Inc

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LONDON, ENGLAND / ACCESSWIRE / January 31, 2024 / Argo Blockchain plc ("Argo" or "the Company"), a global leader in cryptocurrency mining (LSE:ARB)(NASDAQ:ARBK), announces that it has issued 154,475 new ordinary shares of £0.001 each in the capital of the Company ("Ordinary Shares") pursuant to the terms of previously granted Restricted Share Units under the 2022 Equity Incentive Plan approved by shareholders at the Company’s 2022 Annual General Meeting.

The new Ordinary Shares rank pari passu with the existing Ordinary Shares in issue, and application has been made for the shares to be admitted to the Official List and to trading on the Main Market of the London Stock Exchange PLC.

Share Capital and Total Voting Rights

The Company also announces, in compliance with its obligations under Rules 5.6.1R and 5.6.2G of the Disclosure Guidance and Transparency Rules, that as at 31 January 2024, the Company’s share capital consisted of 577,155,838 ordinary shares of £0.001 each (Ordinary Shares). All of the Ordinary Shares have equal voting rights and there are no shares held in Treasury.

The above figure may be used by shareholders as the denominator for the calculations by which they can determine whether they are required to notify their interest in, or a change of their interest in, the Company under the FCA Disclosure Guidance and Transparency Rules.

For further information please contact:

About Argo:

Argo Blockchain plc is a dual-listed (LSE: ARB; NASDAQ: ARBK) blockchain technology company focused on large-scale cryptocurrency mining. With mining facilities in Quebec, mining operations in Texas, and offices in the US, Canada, and the UK, Argo’s global, sustainable operations are predominantly powered by renewable energy. In 2021, Argo became the first climate positive cryptocurrency mining company, and a signatory to the Crypto Climate Accord. For more information, visit www.argoblockchain.com.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: Argo Blockchain PLC

View the original press release on accesswire.com

LONDON, UK / ACCESSWIRE / January 31, 2024 / Ecora Resources PLC (LSE:ECOR)(TSX:ECOR) announces that it has entered into an amendment and extension of its $150 million revolving credit facility agreement with its existing syndicate of Scotiabank, CIBC and RBC. The agreement also includes an uncommitted accordion feature of up $75 million to be used to fund royalty acquisitions which, if implemented, would take the potential borrowing capacity up to $225 million.

The facility has a maturity date of January 2027 with the potential to extend the tenor twice by up to 12 months on each occasion, is largely on the same terms as the previous facility and will be subject to SOFR plus a ratchet between 2.25% and 4.00%, depending on leverage levels.

Commenting on the refinancing, CFO, Kevin Flynn said:

"The continued and enhanced support from our lenders is a strong endorsement of our business and strategy. We have a clear growth strategy and this new facility provides us with additional capacity to continue to build what is the leading portfolio of royalties over commodities essential to a more sustainable future. We are, as always, grateful for the support of our syndicate and look forward to continuing to partner with them as we grow our business."

For further information

About Ecora Resources

Ecora Resources is a leading royalty company focused on supporting the supply of commodities essential to creating a sustainable future.

Our vision is to be globally recognised as the royalty company of choice synonymous with commodities that support a sustainable future by continuing to grow and diversify our royalty portfolio in line with our strategy. We will achieve this through building a diversified portfolio of scale over high quality assets that drives low volatility earnings growth and shareholder returns.

The mining sector has an essential role to play in the energy transition, with commodities such as copper, nickel and cobalt – key materials for manufacturing batteries and electric vehicles. Copper also plays a critical role in our electricity grids. All these commodities are mined and there are not enough mines in operation today to supply the volume required to achieve the energy transition.

Our strategy is to acquire royalties and streams over low-cost operations and projects with strong management teams, in well-established mining jurisdictions. Our portfolio has been reweighted to provide material exposure to this commodity basket and we have successfully transitioned from a coal orientated royalty business in 2014 to one that by 2026 will be materially coal-free and comprised of over 90% exposure to commodities that support a sustainable future. The fundamental demand outlook for these commodities over the next decade is very strong, which should significantly increase the value of our royalty portfolio.

Ecora’s shares are listed on the London and Toronto Stock Exchanges (ECOR) and trade on the OTCQX Best Market (OTCQX:ECRAF).

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: Ecora Resources PLC

View the original press release on accesswire.com

Block Admission Return

MANCHESTER, UK / ACCESSWIRE / January 31, 2024 / THE PEBBLE GROUP PLC

In compliance with the FCA’s Disclosure Guidance and Transparency Rules (the "Rules"), the Company announces that, as at the date of this announcement, it has 167,450,893 Ordinary Shares in issue. The Company does not hold any Ordinary Shares in treasury and all of the Ordinary Shares have equal voting rights.

The figure of 167,450,893 Ordinary Shares represents the total voting rights in the Company and may be used by shareholders as the denominator for the calculations by which they can determine if they are required to notify their interest in, or a change to their interest in, the Company under the Rules.

Enquiries:

About The Pebble Group
The Pebble Group is a provider of digital commerce, products and related services to the global promotional products industry, comprising two differentiated businesses, Facilisgroup and Brand Addition, focused on specific areas of the promotional products market. For further information, please visit www.thepebblegroup.com.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: The Pebble Group PLC

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GOTHENBURG, SWEDEN / ACCESSWIRE / January 31, 2024 / IRLAB Therapeutics (STO:IRLAB-A)(FRA:6IRA), a company discovering and developing novel treatments for Parkinson’s disease, today announced that the company will hold a presentation in conjunction with the publication of the Year-end report for the period January-December 2023. The interim report and presentation will be published on Wednesday, February 7 at 07:00 CET.

The presentation will be held on February 7, 2024, at 10:00 CET via digital webcast. Gunnar Olsson, CEO, Nicholas Waters, EVP and Head of R&D, and Viktor Siewertz, CFO, will comment the Year-end report for 2023. The presentation will be held in English and followed by a Q&A session.

Follow the webcast online: https://www.youtube.com/live/-LGAK3NHUP4?si=9xWvl9JvhGI6e_C3

The interim report and the presentation will be available on www.irlab.se, and the recorded version of the presentation will be available shortly afterward.

For more information

Gunnar Olsson, CEO
Phone: +46 70 576 14 02
E-mail: gunnar.olsson@irlab.se

Viktor Siewertz, CFO
Phone: +46 727 10 70 70
E-mail: viktor.siewertz@irlab.se

About IRLAB

IRLAB is discovering and developing a portfolio of transformative therapies targeting all stages of Parkinson’s disease. The company has its origin in Nobel Laureate Prof. Arvid Carlsson’s research group and the discovery of a connection between the brain’s neurotransmitters and CNS disorders. Mesdopetam (IRL790), in development for the treatment of levodopa-induced dyskinesias, has completed Phase IIb and is in preparation toward Phase III. Pirepemat (IRL752), is currently in Phase IIb, being evaluated for its effect on balance and fall frequency in Parkinson’s disease. In addition, the company is also progressing the three preclinical programs IRL757 (financially supported by the Michael J. Fox Foundation), IRL942, and IRL1117 towards Phase I studies. IRLAB’s pipeline is driven by the company’s proprietary systems biology-based Integrative Screening Process (ISP) research platform. Headquartered in Sweden, IRLAB is listed on Nasdaq Stockholm (IRLAB A). For more information, please visit www.irlab.se.

Attachments

IRLAB: Invitation to the Year-end Report 2023 presentation and webcast

SOURCE: IRLAB Therapeutics

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• MagnetOs Granules becomes the third product in the MagnetOs portfolio to receive FDA clearance to market for interbody use
• Kuros continues expansion of the MagnetOs franchise with launch of MagnetOs Granules and MagnetOs Putty in New Zealand via an exclusive distribution agreement with Vortek Spine Limited, a high-tech orthopedic and biologics company

SCHLIEREN (ZURICH), SWITZERLAND / ACCESSWIRE / January 31, 2024 / Kuros Biosciences ("Kuros" or "the Company"), a leader in next generation bone graft technologies, today announced clearance of a 510(k) submission from the U.S. Food and Drug Administration (FDA) related to its MagnetOs Granules.

The Company also announced clearance to market in New Zealand for MagnetOs Granules and MagnetOs Putty. The products are now commercially available through Vortek Spine Limited ("Vortek"), a high-tech orthopedic and biologics company specializing in healthcare solutions for surgeons and patients. This further expands the MagnetOs portfolio in terms of application and accessibility.

Earlier in January, Kuros announced the FDA clearance of MagnetOs Easypack Putty for interbody use and MagnetOs Putty for standalone use in the posterolateral spine, meaning it can now be used without the need for autograft (patient’s own bone).

"We are very pleased that MagnetOs Granules has received marketing clearance for interbody use given the Granules technology is the foundation of the MagnetOs platform," commented Chris Fair, Chief Executive Officer of Kuros Biosciences. "This clearance, coupled with the MagnetOs Flex Matrix and MagnetOs Easypack Putty formulations, provides our surgeons the widest variety of advanced biologic formulations available for use in the interbody space. We are also very excited to expand our international presence through a partnership with Vortek in New Zealand and to begin working with their team to introduce our clinically proven technology to this territory."

The availability of MagnetOs in New Zealand marks a significant milestone for Kuros and the local medical community since patients can now benefit from an advanced bone graft that improves the overall quality of care in orthopedic and spinal procedures. This benefit was further demonstrated with recent level 1 clinical data in which MagnetOs outperformed the gold standard autograft by 73% in posterior spinal fusion in a difficult-to-treat real life patient population, of which 20% were current smokers. ¹

About MagnetOs

MagnetOs is a bone graft like no other: thanks to its NeedleGrip ^TM surface technology, it grows bone even in soft tissues.* This surface technology provides traction for our body’s vitally important ‘pro-healing’ immune cells (M2 macrophages). ^†‡2,3 This in turn, unlocks previously untapped potential to stimulate stem cells – and form new bone throughout the graft. ^†§4-7 The growing body of science behind NeedleGripTM is called osteoimmunology. But for surgeons and their patients it means one thing: a more predictable fusion. ^†¶6,7

U.S. Indications Statement

MagnetOs Granules is an implant intended to fill bony voids or gaps of the skeletal system, i.e., the extremities, pelvis, intervertebral disc space, and posterolateral spine. These osseous defects may be surgically created or the result of traumatic injury to the bone and are not intrinsic to the stability of the bony structure. When used in posterolateral spine, extremities and pelvis, MagnetOs Granules may be used standalone or mixed with autograft, blood, and/or bone marrow. When used in intervertebral body fusion procedures, MagnetOs Granules must be used with an intervertebral body fusion device cleared by FDA for use with a bone void filler and hydrated with blood. MagnetOs Granules may also be mixed with autograft. MagnetOs Granules resorbs and is replaced with bone during the healing process.

MagnetOs Putty is an implant intended to fill bony voids or gaps of the skeletal system i.e., the extremities, pelvis and posterolateral spine. MagnetOs Putty may be used standalone or mixed with autograft. These osseous defects may be surgically created or the result of traumatic injury to the bone and are not intrinsic to the stability of the bony structure. MagnetOs Putty resorbs and is replaced with bone during the healing process.

MagnetOs Easypack Putty is intended to filly bony voids or gaps of the skeletal system, i.e., the intervertebral disc space, and posterolateral spine. The osseous defects may be surgically created or the result of traumatic injury to the bone and are not intrinsic to the stability of the bony structure. In the intervertebral disc space and posterolateral spine, MagnetOs Easypack Putty must be used with autograft as a bone extender. When used in intervertebral body fusion procedures, MagnetOs Easypack Putty must also be used with an intervertebral body fusion device cleared by FDA for use with a bone void filler. MagnetOs Easypack Putty resorbs and is replaced with bone during the healing process.

MagnetOs Flex Matrix is intended to fill bony voids or gaps of the skeletal system, i.e., the intervertebral disc space, and posterolateral spine. The osseous defects may be surgically created or the result of traumatic injury to the bone and are not intrinsic to the stability of the bony structure. In the intervertebral disc space and posterolateral spine, MagnetOs Flex Matrix must be hydrated with bone marrow aspirate (BMA) and used as an extender to autograft bone. When used in interverterbral body fusion procedures, MagnetOs Flex Matrix must also be used with an intervertebral body fusion device cleared by FDA for use with a bone void filler. MagnetOs Flex Matrix resorbs and is replaced with bone during the healing process.

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RIYADH, SAUDI ARABIA – Media OutReach Newswire – 31 January 2024 – Valuable Capital Financial Company (VCFC), a brokerage firm licensed by the Capital Market Authority (22251-25), announced its corporate name change to Sahm Capital Financial Company (Sahm Capital) effective from January 25, 2024. The announcement comes after its successful launch of the first online trading app Sahm in Saudi Arabia.

“It marks a milestone in Sahm’s journey to become the best online broker in Saudi Arabia. We will remain deeply committed to providing Saudi users with a seamless and tailored investing experience, making investing as simple as breathing,” said Hadeel Bedeeri, General Manager of VCFC.

In October 2023, VCFC received licenses from the Capital Market Authority (CMA) to conduct Dealing, Advising, and Custody services in KSA, making it the first international online brokerage firm to provide online brokerage services in KSA.

In December 2023, the company launched its online trading app Sahm, a proprietary designed and developed specifically for investors in Saudi Arabia. The first of its kind in KSA, Sahm offers users the opportunity to trade in both Saudi and US markets within one app and provides a list of Shariah Compliant Stocks in the US market and a variety of US stock ETFs with Arabic themes.

Sahm app features speedy client account establishment and enables one-click quick switch between Saudi and U.S. stocks accounts in real time for both trading and currency conversion. To accommodate professional traders’ demands, the app also allows users to create Conditional Orders, a synthetic and powerful trading tool previously only seen on professional trading desks.

The Sahm app is now available for download on the iOS App Store, the Android Play Store, and Huawei AppGallery. For more details, visit https://www.alsahm.com

About Sahm Capital

Registered in Riyadh, Sahm Capital (previously known as VCFC) is a joint venture company of Valuable Capital Group Ltd and eWTP Arabia Capital. Sahm Capital is also a registered member of the Saudi Stock Exchange, Tadawul, as well as its affiliates, the Securities Depository Center Company (Edaa) and the Securities Clearing Center Company (Muqassa). The company is also a member of Mena Fintech Association and Middle East Africa and Asia Crypto and Blockchain Association (MEAACBA).

LOS ANGELES, CA / ACCESSWIRE / January 31, 2024 / Tenderize, a trailblazer in the decentralized finance (DeFi) space, is excited to announce the launch of Tenderize Mainnet, marking a new epoch in liquid staking. This launch represents a significant leap forward in the company’s mission to democratize DeFi by breaking free from the traditional constraints of high costs and restrictive practices that have hindered validators and users alike.

Revolutionizing Liquid Staking with Tenderize Mainnet

Tenderize’s mainnet introduces a novel approach to liquid staking, offering a unique Liquid Staked Token (LST) for each validator. This innovative model directly addresses centralization issues, empowering validators with their unique LSTs and fostering a more diversified and decentralized network. This shift not only benefits validators but also allows retail users to stake with their preferred validator, ushering in an era of true decentralization in the DeFi space.

‘The Cookout’ Campaign: Boosting TVL and Community Engagement

The launch is accompanied by ‘The Cookout’ campaign, a strategic initiative designed to boost Total Value Locked (TVL) in Tenderize v2. This campaign allows participants to stake tokens such as $MATIC, $LPT, and $GRT and earn HATS, which are redeemable for the exclusive $WAGYU token.

Empowering Users with Flexibility and Autonomy

In a move that sets Tenderize apart from other protocols, users are given the flexibility to withdraw their liquidity at any time during ‘The Cookout’ campaign. This feature aligns with Tenderize’s ethos of autonomy, transparency, and user empowerment, ensuring participants’ liquidity is not locked in and is available as per their convenience.

Tenderize’s Commitment to a Decentralized Future

With its mainnet, Tenderize is not just launching a protocol; it’s igniting a movement towards a more inclusive and decentralized financial future. The platform’s dedication to creating a user-centric decentralized staking experience is evident in its ability to allow users to create their own index of validator LSTs, offering an unprecedented level of control and customization.

Join the Tenderize Movement

As Tenderize Mainnet goes live, the company invites everyone to be part of a movement that’s reshaping the world of liquid staking. Backed by over millions in TVL, more than 40 validator partners, and support from notable entities such as Eden Block, Figment, and TRGC, Tenderize is well-positioned to be a catalyst for a decentralized and equitable financial future. The team, comprising experts from organizations like Livepeer, Sperax, Ankr, Helio CDP, and Forbes, is at the forefront of this transformative venture.

For more information on Tenderize, follow Tenderize on X (Formerly Twitter) for real-time updates, explore the comprehensive Whitepaper, and edplore the docs on how to participate in ‘The Cookout’ campaign. For all other information on the Tenderize platform, please visit https://tenderize.me/

Media Contact

Organization: Tenderize Labs
Contact Person: Nicholas Resendez
Website: https://www.tenderize.me/
Email: alec@tenderize.me
City: Los Angeles
State: California
Country: United States

SOURCE: Tenderize Labs

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NEW YORK, NY / ACCESSWIRE / January 30, 2024 / Online education resource Financially Lit Academy has announced the upcoming launch of a new workbook designed to accompany the company’s children’s book, "The ABCs of Wealth Building". The workbook is set to launch in January 2024 in concert with a series of seminars scheduled for the same month.

Both the original book and the pending workbook were written by the company founder and CEO Tanisha Adjokatcher, along with co-writer Chyanne Adjokatcher. Tanisha Adjokatcher will also be leading the series of online financial literacy seminars in January. While "The ABCs of Wealth Building" and the accompanying upcoming workbook are directed at children 5th grade and above, Adjokatcher’s seminars primarily focus on teaching financial literacy to parents and students. The seminars in early 2024 will be directed at adults, teaching them both financial skills and how to teach their own children the basics of finances.

Financially Lit Academy is also bolstering its selection of online courses, which are designed to help users boost their income streams and teaches the essentials of building a business, building wealth, and leaving a financial legacy for their children. The company offers coaching and encourages independent thinking in its clients, promoting a shift in mindset with the goal of opening up new perspectives and encouraging a future-oriented approach to finances.

The newly expanded courses have helped past clients to set up successful businesses, achieve personal financial growth, learn savvy credit management, learn how to navigate Amazon to make money, and participate in ecommerce ventures. Financially Lit Academy has been recognized for ecommerce achievements, entrepreneurial excellence, and significant online customer engagement.

Key to Financially Lit Academy’s updated offerings is its comprehensive credit & funding education services, which include a step-by-step credit repair program, various tools for debt elimination and expense minimization, and strategies for income growth. The Academy’s ecommerce training is particularly noted for its thorough approach to enhancing financial literacy by setting up a business structure, understanding branding and marketing, featuring instructional videos, step by step training.

Financially Lit Academy also specializes in aiding small businesses, often providing financial solutions where traditional banks may not. The academy offers strategic funding plans, helping clients secure unsecured loans, lines of credit, and revolving lines, thus assisting businesses in gaining access to the right funding sources for their needs.

CEO Tanisha Adjokatcher states that her experiences in creating her online courses, working as a coach and mentor, and her experience as a Minority/Women-owned Business Enterprise (MWBE) certified entrepreneur and Department of Education (DOE) vendor/contractor have shown her a gap in the educational system: teaching financial literacy to children. That is what inspired her to write "The ABCs of Wealth Building", along with the upcoming accompanying workbook.

"There is a need for improved financial literacy," says Adjokatcher, pointing to research that demonstrates this need. As of 2023, only 57% of adults in the US are financially literate; Americans lose an average of $1,819 every year due to financial illiteracy; and 77% of Americans report feeling anxious about their finances.

"I believe that financial literacy should be taught from early childhood, and should be available and accessible to everyone," says Adjokatcher. "My goal with ‘The ABCs of Wealth Building’ is to get a copy into the hands of every school, every library, and as many parents as possible. The book was designed to simplify complex financial concepts, breaking them down to a child’s level, and using interactive exercises and colorful illustrations to make learning fun and engaging."

The upcoming workbook will have a range of exercises and worksheets to accompany the book. Adjokatcher feels that offering financial education to kids should be designed to meet them where they are. Storytelling, stickers, interactive role-play, vision boards, and other engaging tactics help kids get excited about learning and this education has the potential to kick-start their financial success in the future.

About Financially Lit Academy

Financially Lit Academy is an educational platform dedicated to enhancing financial literacy in both children and in adults. The academy offers an array of services such as credit education, income growth strategies, and investment guidance. The company offers online courses, interactive workshops, and personalized coaching. CEO and founder Tanisha Adjokatcher has also written a children’s book, "The ABCs of Wealth Building", to promote financial literacy in young students.

Learn more: http://tanishamarie.com/

Contact:
Tanisha Adjoatcher
7018003209
successlevelmarketingteam@gmail.com

SOURCE: Financially Lit Academy

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